The San Francisco 49ers (5-0) and the Cleveland Browns (2-2) meet on Sunday for a Week 6 matchup at Cleveland Browns Stadium. Kickoff is scheduled for 1 p.m. ET (FOX). Below, we look at 49ers vs. Browns odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.
The 49ers remain 1 of 2 unbeaten teams in the NFL after dismantling the Dallas Cowboys 42-10 on Sunday Night Football. RB Christian McCaffrey scored a touchdown in his 14th straight game.
The Niners have scored 30 or more points in every game this season, including a 30-7 road win against the Pittsburgh Steelers in Week 1, an AFC North Division opponent.
The 49ers easily covered against the Cowboys, and they’re now 4-1 against the spread (ATS), with covers in 3 straight. The Over has cashed in back-to-back games, and 3 of the past 4 outings. The Under cashed in Week 1 in the 1st meeting vs. an AFC opponent.
The Browns are coming off a bye week. QB Deshaun Watson missed the game prior to the bye due to a shoulder injury. He is expected to be ready for Week 6. Cleveland has alternated wins and losses in the first 4 weeks, while also alternating covers and non-covers. The Under is 3-1 in 4 outings. This is Cleveland’s 1st game vs. an NFC foe this season.
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49ers at Browns odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 6:11 a.m. ET.
- Moneyline (ML): 49ers -188 (bet $188 to win $100) | Browns +158 (bet $100 to win $158)
- Against the spread (ATS): 49ers -3.5 (-110) | Browns +3.5 (-110)
- Over/Under (O/U): 41.5 (O: -105 | U: -115)
2023 betting stats
- ML: 49ers 5-0 | Browns 2-2
- ATS: 49ers 4-1 | Browns 2-2
- O/U: 49ers 3-2 | Browns 1-3
49ers at Browns head-to-head
These teams haven’t met since Oct. 7, 2019, a 31-3 victory by the 49ers at Levi’s Stadium in Santa Clara.
The last time these teams met at Cleveland Browns Stadium, the Browns picked up a 24-10 win with Johnny Manziel at QB as 2.5-point favorites as the Under (43) cashed on Dec. 13, 2015.
The home team has won and covered each of the past 4 games in the series. The last time the road team won was a 13-12 win by the Browns in Candlestick Park on Sept. 21, 2003.
This will the 30th all-time meeting with the Browns leading 19-10.
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